I played TR and Wish. But got only one replacement card, instead of two cards. Was this due to the fact that wish goes back into the supply (or pile of unused/returned Wishes) and therefore could not be 'found' for the second playing via TR? Or, was it a true bug?
There are, by now--with so many expansions, a good number of cards that do not play nicely with KC and TR. And other cards that are wasted if used as a duration card, and so on. It would be great to have a pop-up window that shows up when a player tries these types of combos. [e.g., for my attempt of TR + Wish: "Throne Room will have no effect on the card [wish]. Do you want to (a) Undo and select a different card, or (b) Continue with this combo]?" I have no idea if this would be easy to code, if it would be doable, but a bit of a pain, or, if it would be horribly complicated and intrusive to code.
I suspect that there will be future Dominion expansions, ever-more-complicated and nuanced cards, and so "interesting" interactions will happen more and more frequently.
If I am playing Lord Rat, then I don't really care if somethings happens that I did not expect from a card's wording...even if that confusion is what lost the game for me. But it matters more in real-life games, since the only solution is to tell the other player in Chat, "Um, I thought this combo would be allowed, but Dominion says No. Can I undo and try a different card combo that actually will be allowed?"
I would bet that if you threw this question open to players (ie, "What card combos do not work as you expect from the card's wording? What popup warning/instruction would be helpful to have in that specific case(s)"; you'd get a fairly accurate and extensive list pretty quickly.)